Stimulant medications are the first-line drugs in adults with ADHD. Adderall is a combination of dextro-amphetamine (75%) and levo-amphetamine (25%). It comes in Immediate Release (IR) and Extended Release (XR) formulations. The XR formulation provides the equivalency of two IR tablets ingested four hours apart, so that Adderall XR 20 mg once daily is equivalent to Adderall IR 10 mg twice daily.
The XR capsule contains an IR formulation, plus a delayed IR formulation. It is not uncommon for users to notice a reduction in blood levels of the drug between the two doses. This is true for both formulations.
The Drug Enforcement Agency (DEA) categories drugs based on their potential for abuse/dependence. Schedule I drugs are considered to have a high potential for abuse and no accepted medical benefit. Adderall and other stimulant medications for ADHD are Schedule II drugs.
- Schedule I: LSD, Marijuana, Methamphetamine, Heroin, MDMA, PCP. Peyote
- Schedule II: Ritalin, Vyvanse, Adderall, Morphine, Oxycodone, Hydrocodone.
- Schedule III: Suboxone, Anabolic steroids, ketamine
- Schedule IV: Valium, Xanax, Klonopin, Ambien, Provigil, Nuvigil, Tramadol
- Schedule V: Lyrica
Brand Name: Adderall, Adderall XR
Generic Name: Amphetamine-Dextroamphetamine, Amphetamine-Dextroamphetamine XR
Habit Forming: Amphetamines have a high potential for abuse; prolonged administration may lead to dependence. However, typical oral doses of Adderall do not usually produce euphoria and are not usually addicting.
Pregnancy: Risk Category C (animal studies do not show adverse effects, but no controlled studies in humans).