Methylphenidate for ADHD

Methylphenidate is a central nervous stimulant that is structurally similar to amphetamine.  It functions as a norepinephrine and dopamine reuptake inhibitor.  Improvements in attention, memory, and motor function occur with use.

It was created in Switzerland over sixty years ago.

Brand Name:  Ritalin, Concerta

Generic Name: Methylphendiate

Pharmacology: Methylphenidate is thought to block the reuptake of norepinephrine and dopamine into the pre-synaptic neuron and increase the release of these neurotransmitters into the extra-neuronal space.

Contraindications: Glaucoma, Tics, Co-administration with MAO Inhibitors,

Dosage Forms: 18 mg, 27 mg, 36 mg, 54 mg, 72 mg

Dosing Range:

Methylphenidate Hydrochloride Extended-Release (SpecGx LLC): FDA ...

Habit Forming: Schedule II medication.  High risk for dependence.

Pregnancy:  Risk Category C (animal studies do not show adverse effects, but no controlled studies in humans).

Drug Interactions:

Methylphenidate is generally well tolerated, but like all medications, it may cause side effects.

Methylphenidate Research