Methylphenidate for ADHD
Methylphenidate is a central nervous stimulant that is structurally similar to amphetamine. It functions as a norepinephrine and dopamine reuptake inhibitor. Improvements in attention, memory, and motor function occur with use.
It was created in Switzerland over sixty years ago.
Brand Name: Ritalin, Concerta
Generic Name: Methylphendiate
Pharmacology: Methylphenidate is thought to block the reuptake of norepinephrine and dopamine into the pre-synaptic neuron and increase the release of these neurotransmitters into the extra-neuronal space.
Contraindications: Glaucoma, Tics, Co-administration with MAO Inhibitors,
Dosage Forms: 18 mg, 27 mg, 36 mg, 54 mg, 72 mg
Dosing Range:
Habit Forming: Schedule II medication. High risk for dependence.
Pregnancy: Risk Category C (animal studies do not show adverse effects, but no controlled studies in humans).
Drug Interactions:
Methylphenidate is generally well tolerated, but like all medications, it may cause side effects.