Naltrexone for Alcoholism

FDA-approved medication for Alcohol Use Disorders

Brand Name:  ReVia. Vivitrol (injection).

Generic Name: Naltrexone \nal-ˈtrek-ˌsōn\

Pharmacology:  Naltrexone blocks opioid receptors, preventing opiate medications, heroin, and endorphins from having effects.  

Contraindications:  Liver disease.  Recent use of opiates.

Dosage Forms:  50 mg tablet.

Dosing:  25 mg for two days and then 50 mg thereafter as tolerated.

Maximum Dose:  100 mg daily.

Habit Forming:  No

Pregnancy:  Risk Category C (animal studies do not show adverse effects, but no controlled studies in humans).

Naltrexone Research

The u-Opioid Receptor and Treatment Response to Naltrexone

Views about responsibility for alcohol addiction and negative evaluations of naltrexone

Internest Sex Addiction Treated with Naltrexone

Effects of Naltrexone on Smoking Cessation Outcomes and Weight Gain in Nicotine-Dependent Men and Women

Targeted Use of Naltrexone Without Prior Detoxification in the Treatment of Alcohol Dependence: A Factorial Double-Blind, Placebo-Controlled Trial

Improving clinical outcomes for naltrexone as a management of problem alcohol use