The U.S. Food and Drug Administration or FDA is also taking interest in the research on psilocybin. Moreover, it has approved the conducting of bigger-scale studies with regards to the usefulness of psilocybin in treating severe depressive disorder and TRD.
So, what makes psilocybin so powerful? Current data suggest that it might be able to modify the mind. Moreover, it produces a psychologically modified state wherein there is an altered state of mind and the hurdles to exploring old traumas are lifted, although temporarily.
There is an impact of the drug on the individual’s serotonergic system. According to MRI scans, it causes an increase in the neuronal repartee between different regions of one’s brain. So, these are regions that don’t usually communicate with each other.
Psilocybin-based psychotherapy is preferred in a favorable setting. The patient lies on a couch-type of seating with music playing in the background (they need to wear eyeshades for the session).
The setting aims to facilitate an emotional breakthrough. And it typically leads to antidepressant effects, stress relief and mood improvement. These effects are for over six months.